Centro de estudios sobre déficit atencional infantil

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Asociación civil sin fines de lucro dedicada a la investigación del síndrome de hiperactividad y déficit de atención

Novedades científicas

Current Literature in ADHD

 

Summarized by Sam Goldstein

 

Barton, B., & North, K. (2004).

Social skills of children

with Neurofibromatosis Type I.

Developmental Medicine

and Child Neurology, 46, 553-563.

 

The reported incidence of ADHD in

Neurofibromatosis Type I (NF1) is higher than in the general

population. In this study of 79 children of mixed gender,

39% met diagnostic criteria for ADHD. This study

investigated the social skills of children with NF1 and the

influence of comorbid conditions, such as ADHD. Children

with NF1 had significantly poorer social outcomes

than their unaffected siblings and significantly poorer

social skills in comparison with normative data. The presence

of ADHD was the major risk factor for poor social

functioning. Children with NF1 and ADHD had poor

social skills and social outcomes when compared with

children with NF1 only or children with NF1 and learning

difficulties. Thus, it would appear that it is ADHD and not

NF1 alone that is associated with poor social functioning.

 

Gerdes, A. C., Hoza, B., & Pelham, W. (2003).

ADHD boys’ relationships with their mothers and fathers: Child,

mother and father perceptions.

Development and Psychopathology, 15, 363-382.

 

The accuracy of children’s self-perception in family

relationships was evaluated in this study that compared

142 males with ADHD and their parents to 55 controls

and their parents. The authors hypothesized that the children

with ADHD would rate their relationships with their

parents as inflated in comparison to the actual ratings provided

by parents. Mothers and fathers of boys with

ADHD perceived their parent-child relationships more

negatively than did parents of control boys. Ratings provided

by the children, however, did not differ from one another. Boys with ADHD rated their relationships with their parents more highly than did parents. Ratings given by mothers and fathers were not different from each other.

The authors concluded that if children with ADHD are unaware of disruptions in their relationships, then treatment should target skill deficits as well as accuracy of perception.

 

Larsson, J., Larsson, H., & Lichtenstein, P. (2004).

Genetic and environmental contributions to stability and

change of ADHD symptoms between eight and thirteen

years of age: A longitudinal twin study.

Journal of the American Academy of Child and Adolescent Psychiatry,

43, 1267-1275.

 

This sample included nearly 1,500 twin pairs born in

Sweden in the mid-1980s. Structural equation modeling

was used to analyze checklist data based on the Diagnostic

and Statistical Manual of Mental Disorders (3rd ed.,

revised) symptoms for ADHD. The authors found a relatively

high stability of ADHD symptoms during a 5-year

period. The continuity was mainly caused by the same

genetic effects operating at both points in time. Change in

symptoms between childhood and adolescence was to a

large extent caused by new genetic effects in early adolescence

and new nonshared environment effects that

became important during the adolescent years. The

authors noted a heritability estimate for ADHD at 74%

for males and 61% for females. This would appear to be

the first longitudinal data from a nonreferred,

nonmedicated sample. The factors associated with resilience in peer-rejected

females with and without ADHD were evaluated in this

study of 91 females with ADHD and 58 female controls

between the ages of 6 and 12.5 years. The authors sought

to determine whether positive relationships with adults

and goal-directed solitary play served as functional substitutes

for peer relationships. Sociometric ratings and

staff popularity ratings for each female were obtained on

multiple occasions. Direct behavioral observations were

also completed for multiple occasions. Outcome measures

included aggressive as well as depressed and anxious

behaviors. Peer rejection was related to higher levels

of aggressive, depressed, and anxious behavior. For

rejected and nonrejected females, popularity with adult

staff members was associated with lower levels of aggressive

behavior, whereas goal-directed solitary play was

associated with lower levels of depressed and anxious

behavior. This effect was greatest for females with ADHD.

Among rejected females, goal-directed solitary play was

the most protective, whereas popularity with adults was

most protective in the nonrejected group. The authors

conclude that engaging in goal-directed solitary play

appears to be a protective factor against the negative internalizing

outcomes of peer rejection for females with

ADHD in particular. The authors suggest that programs

for peer-rejected children should include such protective

factors as teaching solitary play activities in addition to

traditional social skill components.

 

Riccio, C. A., Wolfe, M. E., Romine, C., Davis, B., &

Sullivan, J. R. (2004).

The Tower of London in neuropsychological

assessment of ADHD in adults.

Archives of Clinical Neuropsychology, 19, 661-671.

 

Current theories of ADHD have increasingly focused

on executive functions, particularly those related to planning,

strategy, and working memory, as well as the maintenance

of attention in the pursuit of specific goals. It is

suggested that these behaviors are deficient in individuals

with ADHD. The Tower of London is one task used in the

assessment of executive functions. These authors evaluated

102 individuals between the ages of 16 and 33 for the

Tower of London performance, along with other executive

measures. Based on diagnostic considerations, nearly

2% of this sample met the diagnostic criteria for ADHD.

It is interesting that more than half presented with

comorbid conditions, including depression and learning

disability. The results suggested that although the Tower

of London measured aspects of ability likely not tapped

by other executive neuropsychological measures and

therefore may provide additional information concerning

individual functioning, findings between these groups

were equivocal, suggesting that the Tower of London is not

an instrument that adults with ADHD are unable to complete

successfully.

 

Sawyer, M. G., Rey, J. M., Arney, F. M., Whitham, J. N.,

Clark, J. J., & Baghurst, P. A. (2004).

Relationship between parents’ perceptions of children’s need for professional help.

Journal of the American Academy of Child

and Adolescent Psychiatry, 43, 1355-1363.

 

The impact of children’s problems on children and parents

and services used during a 6-month period were

examined in a national sample in Australia of nearly 400

children and teens with ADHD symptoms between the

ages of 6 and 17. Only 28% of those with ADHD symptoms

had attended health-or school-based services.

Forty-one percent had attended both health-and school-

based services. Thirty-nine percent had attended only

health-based services, and 20% had attended only school-

based services. Sixty-nine percent of parents attending

health-based services wanted additional help. Parent perceptions

that children required professional help, the children’s

level of functional impairment, the impact of problems

on parents, and comorbid, depressive, or conduct

disorders had significant and independent relationships

with service use. It appears that factors other than children’s

ADHD symptoms have a significant relationship

with service attendance.

 

Schwartz, G., Amor, L. B., Grizenko, N., Lageix, P.,

Baron, C., Boivin, D., et al. (2004).

Actigraphic monitoring during sleep of children with ADHD and methylphenidate and placebo.

Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1276-1282.

 

Nightly sleep actigraphic recordings during a double-

blind, placebo-controlled, cross-over clinical study were

obtained on 44 children with ADHD. Significant differences

between conditions were found in several software-

computed parameters, including sleep onset latency,

sleep efficiency, and total sleep time. No significant differences

on any of these measures were found between

the 26 participants who showed a moderate to large global

improvement on methylphenidate over placebo and the

18 participants who showed mild or no clinical improvement.

The authors concluded that twice daily dosing of

methylphenidate induced a slight but significant sleep

disturbance. Motor activity levels during sleep did not differentiate

children who responded to methylphenidate

from those who did not. The authors suggest that the

responders to methylphenidate treatment do not experience

greater sleep disturbance than do the nonresponders

for the doses studied.

 

Singh, I. (2003).

Boys will be boys: Fathers’ perspectives

on ADHD symptoms, diagnosis and drug treatment.

Harvard Review of Psychiatry, 11, 308-316.

 

Thirty-nine mothers and 22 fathers of males with

ADHD were interviewed by using a novel, picture-based

method to elicit detailed narratives. The authors suggest

that paternal perspectives on ADHD behavior, diagnosis,

and drug treatment could be largely categorized as skeptical,

characterizing these fathers as reluctant believers or

tolerant nonbelievers. Fathers generally tended to resist

the medical framework in relation to their sons’ behavior.

The author emphasized that an evaluation lacking the perspective

of the child’s father is incomplete and may lead

to failure of proven treatments to work effectively.

 

Tamm, L., Menon, V., Ringel, J., & Reiss, A. (2004).

Event-related fMRI evidence of frontal temporal involvement

in abhorrent response inhibition and task switching in ADHD.

Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1430-1440.

 

Response inhibition deficits are characteristic of individuals

with ADHD. This study was designed to develop

an understanding of the neurocorrelates of response inhibition.

Ten adolescent boys with ADHD (combined type)

and 12 typically developing controls completed go–no go

tasks modified to control for novelty processing. The

group with ADHD made significantly more errors of

omission and more errors of commission than the control

group. Compared with the controls, those with ADHD

showed marked abnormalities in brain activation during

response inhibition, including hypoactivation of the anterior

and midcingulate cortex extending to the supplementary

motor area and hyperactivation of the left temporal

gyrus. It would appear that underactivation in the frontal

regions reflects core deficits in response and task

switching abnormalities for individuals with ADHD.

 

Unnever, G. D., & Cornell, D. G. (2003).

Bullying, self-control and ADHD.

Journal of Interpersonal Violence, 18, 129-147.

 

These authors examined a group of middle school students

relative to bullying, bully victimization, ADHD,

and student physical characteristics. A population of

more than 1,300 sixth through eighth graders completed a

series of questionnaires. Students reported the frequency

with which they had engaged in or been the target of areas

of bullying behaviors. Students were also asked whether

they had ever taken medication for ADHD. Fourteen percent

of the population reported a past history or current

use of medication to treat ADHD. Prior use of medications

for ADHD significantly and directly predicted bullying

victimization. In a group of youth with self-reported

ADHD, 34% experienced victimization compared to

22% of other students. Obesity, comorbid to ADHD,

increased in the risk of bullying victimization. Thirteen

percent of students with ADHD reported bullying others

compared 8% of other students. Bullying was most

closely related to reports of low self-control, obesity, and

height. The relationship between ADHD and victimization

is not unexpected in light of the fact that many

children with ADHD struggle socially, making them an

easy target for bullies.